NovaBiotics Ltd

NovaBiotics Ltd is a leading, clinical-stage biotechnology company focused on developing novel, immune-based therapies for medically unmet, life-threatening and life-limiting diseases. The Company's robust pipeline includes clinical stage antimicrobials that have been derived from NovaBiotics' proprietary anti-infective peptide platform and a "mini biologic" antibacterial-mucolytic compound (Lynovex®). NovaBiotics has developed NP213 (Novexatin®) as a topical treatment for fungal nail infections (onychomycosis), a condition that affects more than 10% of the global population. This first-in-class antifungal agent is expected to be launched as 1x daily, 28-day duration brush-on-treatment for onychomycosis in 2022. NovaBiotics' NM001 (Lynovex®) is an orphan drug treatment for cystic fibrosis. NM001 has a unique dual antibacterial-mucoactive mode of action that kills bacteria, disables biofilms and disrupts excess mucous produced in the airways of patients with cystic fibrosis (and other chronic respiratory diseases). NM001 is being evaluated in Phase IIa clinical trials as an oral treatment for cystic fibrosis and is also being formulated for inhalation to enable longer term, more targeted delivery of the drug. An exciting pipeline of preclinical stage drug candidates is already demonstrating significant promise. These include NP339 (Novamycin®), an antifungal peptide agent against Candida spp and other clinically relevant yeasts and molds as well as NP432 (Novarifyn®), a peptide antibacterial for difficult to treat multi-drug resistant Gram-negative and Gram-positive infections. A leading innovator in the sector, NovaBiotics has a robust IP portfolio of granted and pending patents which are wholly owned by the Company. NovaBiotics is a privately held company, based in Aberdeen, UK and has raised approximatelyf £25 million in equity investment since its foundation in 2004.