Bennette Attipoe
About
Bennette Attipoe is from Philadelphia, Pennsylvania, United States. Bennette works in the following industries: "Biotechnology Research". Bennette is currently Associate Scientist at Chimeron Bio, located in United States. In Bennette's previous role as a Scientist at The Janssen Pharmaceutical Companies of Johnson & Johnson, Bennette worked in United States until Apr 2021. Prior to joining The Janssen Pharmaceutical Companies of Johnson & Johnson, Bennette was a Research Specialist at University of Pennsylvania School of Medicine and held the position of Research Specialist at Greater Philadelphia Area. Prior to that, Bennette was a Graduate Research Student at The Campbell Lab, Drexel University, College of Medicine., based in Greater Philadelphia Area from Nov 2015 to Aug 2017. Bennette started working as Management Trainee - Diageo Early Career Programme at Guinness Ghana Breweries PLC (Diageo) in United States in Mar 2012. From Jan 2010 to Apr 2012, Bennette was Biochemist at Biogas Technologies Africa Limited, based in Accra, Ghana.
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Bennette Attipoe's current jobs
Bennette Attipoe's past jobs
I worked on developing a protein-based therapy, sFRP2, for treating sex-specific sudden cardiac death. I studied the effects of this protein on cardiac disease and fibrotic markers. I applied gene expression studies to identify new mechanisms, pathways, and druggable targets for the development of novel therapies, mainly using in vivo models of cardiovascular diseases and in vitro systems. I developed control cell lines, using lentiviral expression systems, to probe into the role of Cyclase Associated Protein 2 (CAP2) in sudden cardiac death. I also studied drug resistance mechanisms in Neurofibromatosis type 1 and Neurofibromatosis type 2 tumors, by employing High Throughput Screening and qPCR technologies. In addition to my core responsibilities, i mentored students in the Teen Research and Education in Environmental Science (TREES) program at the Center of Excellence in Environmental Toxicology, University of Pennsylvania on how to apply scientific methodology to solve real-world problems.
My research work at the Campbell lab was aimed at understanding the role of CXCL-CXCR2 signaling in the modulation of stromal fibroblast recruitment in pancreatic cancer. I was able to show that migratory characteristics of fibroblasts in pancreatic tumor microenvironments, modulated by the CXCR-CXCL signalling axis, was a potential cause of the dense stroma observed in pancreatic cancer. My studies enabled me to improve migration assay protocols for research aimed at understanding the paracrine signaling effects cancer cells have on their microenvironment. I also contributed to understanding the possible role of the human antigen R protein (HuR), which is an mRNA binding protein, which plays a role in pancreatic cancer progression.
I was part of the supply chain graduate programme which was aimed at growing expertise in how Diageo products are made, optimization of manufacturing processes, and marketing of finished products to customers. As a member of the supply chain team, i coordinated the design and execution of a market research plan which helped identify lapses in product promotions, volumes, and distribution that were impacting Diageo’s product market share in Ghana.