Charlene Trilleaud
About
Charlene Trilleaud is from Rezé, Pays de la Loire, France. Charlene works in the following industries: "Biotechnology Research". Charlene is currently Junior Scientist at OSE Immunotherapeutics, located in Nantes, Pays de la Loire, France. In Charlene's previous role as a Researcher PhD Student at OSE Immunotherapeutics, Charlene worked in Région de Nantes, France until May 2020. Prior to joining OSE Immunotherapeutics, Charlene was a Masters Student at Effimune and held the position of Masters Student at Région de Nantes, France. Prior to that, Charlene was a Masters Student at Institut gustave roussy, based in Paris, Ile-de-France, France from Mar 2015 to May 2015. Charlene started working as Bachelor Student at Institut de Recherche en Santé in Région de Nantes , France in Jun 2014.
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Charlene Trilleaud's current jobs
Charlene Trilleaud's past jobs
Development and characterization of an anti-ChemR23 mAb targeting resolution pathways in chronic inflammatory diseases. - Developed and evaluated the preclinical effect in various mouse models : acute and chronic colitis models (DSS, TNBS, CD45RBhigh, IL10-KO), auto-immunity models (Aldara, T1D, EAE), inflammation models (peritonitis, air-pouch, LPS) and oncology (CT26, MC38, 4T1, LLC). - Designed and analyzed different in vitro functional assays : apoptosis, phagocytosis, MLR, Live&Dead, calcium mobilization - Phenotyping assess by multiparametric flow cytometry - Performed cytokines secretion by ELISA and signaling pathways by WB and microscopy - Human PBMC isolation and culture and mouse tissue handling (colon, spleen, bone marrow, brain, pancreas) - Generated human and mouse macrophages and DC - Wrote and corrected scientific articles, patents and project reports - Presentation research in congress and team and lab meetings
Characterization of an anti-ChemR23 mAb effect in human an mouse cells populations - Developed and evaluated the preclinical effect in divers mouse models : acute colitis (DSS, TNBS), inflammation (peritonis), psoriasis like models and oncology model (4T1). - Performed cytokines secretion by ELISA and signaling pathways by WB - Multiparametric flow cytrometry
PCNA monoubiquitination study during somatic hypermutation - Analyzed of protein expression by WB - Culture of B cell lines - Evaluated cell cycle by IP - Flow cytometry