Dipankar Manna
About
Dipankar Manna is from Oslo, Oslo, Norway. Dipankar works in the following industries: "Wellness and Fitness Services". Dipankar is currently Scientist - Vaccine Discovery at Nykode Therapeutics, located in Oslo, Norway. In Dipankar's previous role as a Visiting Scientist at CALPRO AS, a Svar Life Science company, Dipankar worked in Oslo, Norway until Nov 2021. Prior to joining CALPRO AS, a Svar Life Science company, Dipankar was a Researcher at University of Oslo (UiO) and held the position of Researcher at Oslo Area, Norway. Prior to that, Dipankar was a Postdoctoral Fellow at University of Oslo, based in Oslo Area, Norway from Aug 2016 to Aug 2019. Dipankar started working as Graduate Student Researcher at University of Oslo in Oslo Area, Norway in Aug 2013. From Dec 2014 to May 2016, Dipankar was Guest Student Researcher at The Norwegian Radium Hospital, based in Oslo Area, Norway. Prior to that, Dipankar was a Visiting Student Researcher at ETH Zurich, based in Zürich Area, Switzerland from Jun 2015 to Jul 2015. Dipankar started working as Research Scientist, Protein Science & Drug Discovery at Aurigene Discovery Technologies Limited in Bangalore, India in Feb 2011.
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Dipankar Manna's current jobs
Dipankar Manna's past jobs
Purification of calprotectin from neutrophils (blood cells) in it's native state and characterization of its biochemical properties to use as a molecular marker for the IBD.
I am working as a Research with Prof. Ute Krengel’s group at the Department of Chemistry. At the same time I am involved in teaching Protein Crystallography course (KJM4350/9350- Spring 2021). My project is focused on the structural characterization of cytolethal distending toxin (CTD) produced by the gram-negative pathogen Haemophilus ducreyi. - Evaluated the role of bacterial toxins in human diseases - Performed & optimized toxin production protocol and its characterization - Provided assistance in research, experimentation & data analysis
As a Postdoctoral Fellow at the Department of Molecular Medicine, Faculty of Medicine I had such a wonderful experience working with a fascinating project aimed to develop new therapy and diagnosis for Stroke. - Accelerated the development of new therapy & diagnostics for stroke - Expressed, produced & characterized recombinant proteins to use as therapy - Managed project with internal & external collaborators and colleagues - Trained & supervised lab technicians to ensure necessary skill development - Published two research papers as co-author, one more will publish soon
It was a great opportunity to work with Prof. Ute Krengel’s group at the Department of Chemistry. I joined the group as a PhD student and my project was to study fungal chimerolectins (protease) and define their role in fungal defense using structural biology as tool. Thesis Title: "Structure-function characterization and toxicity studies of fungal chimerolectins" - Successfully investigated & unfolded the role of proteases in diseases - Developed & optimized protein expression, purification & characterization - Successfully crystallized & solved four protein crystal structures - Documented experimentation, analyze data & recorded results - Computational programs- CCP4i, XDS, iMosfilm, MolProbity, MolRep, bioinformatic tools - Published three research articles as first author, in peer-reviewed journals
As part of my PhD collaboration, I got an opportunity to work with Prof. Kirsten Sandvig’s group at the Radium Hospital, Oslo. I have performed several toxicity assays of the protease (of which I already solved the crystal structure) on different mammalian cancer cells and studied its effect on cellular structural components using microscopy.
I worked in the laboratory of Prof. Markus Künzler (Markus Aebi Lab.) at the Institute of Microbiology, ETH, Zürich. It was part of my PhD program and Markus was our international project collaborator. During my two months stay at ETH, I have studied the toxicity effect of protease in model organisms- C. elegans and Drosophila. Also I have performed Mass spectrometry analysis to determine the substrate specificity of the protease at the University of Zürich.
- Actively contributed to novel structure-based drug discovery projects - Conducted extensive lab work designing, experimentation & data analysis - Communicated with management & other departments concerning progress & results of projects; collaborated & coordinated with cross functional teams - Represented the company in conferences, trade shows & science forums
Build sales roadmap in line with sales target and initiated promotional activities for new products. Identified and reviewed client’s requirement in order to provide tailored solutions. Expanded client base by setting up regular meetings, presentations and follow-up. Provided customer training and consultations. Worked on CRM system and achieve territorial business goals.
I started my research career in the laboratory of Prof. Amit K. Das at the Department of Biotechnology at Indian Institute of Technology (IIT), Kharagpur. - Investigated the role enzymes in Staphylococcal infection - Learned & adopted necessary biochemical techniques in protein biochemistry - Developed & optimized protocols for protein production & purification - Maintenance and technical assistance to the in-house Rigaku diffractometer facility
Worked on both new and existing customers to discuss requirements, negotiate terms and maximize business opportunities. Built and retained long-term relationship with customers. Acted as key point of contact for the company and ensured a high standard of customer service. Achieved monthly/quarterly revenue targets.
- Planned lessons & taught students - Established positive relationship with students to facilitate good learning - Prepared & assessed students for exams, motivated them to succeed - Participated & contributed to administrative roles and departmental meeting.