Lois Tolvinski
About
Lois Tolvinski is from Philadelphia, Pennsylvania, United States. Lois works in the following industries: "Biotechnology Research". Lois is currently Director Laboratory Operations at Vivodyne, located in Philadelphia, PA. Lois also works as Chair, Chapter Leaders at LabOps Unite Community, a job Lois has held since Aug 2025. Another title Lois currently holds is Co-Chair, Philadelphia Chapter at LabOps Unite Community. In Lois's previous role as a Senior Manager, Laboratory Operations at Vivodyne, Lois worked in Philadelphia, PA until Apr 2026. Prior to joining Vivodyne, Lois was a Co-Chair, Research Committee at LabOps Unite Community and held the position of Co-Chair, Research Committee. Prior to that, Lois was a Manager, Laboratory Operations and Manufacturing/Bioprocess Development at Chimeron Bio, based in Philadelphia, Pennsylvania, United States from Feb 2022 to Oct 2023. Lois started working as Scientist at Chimeron Bio in Philadelphia, Pennsylvania, United States in Jan 2021. From Apr 2020 to Jan 2021, Lois was Associate Scientist at Chimeron Bio. Prior to that, Lois was a Scientist II at The Janssen Pharmaceutical Companies of Johnson & Johnson, based in Spring House, PA from May 2018 to Mar 2020. Lois started working as Business Development Intern at The Wistar Institute in Oct 2017.
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Lois Tolvinski's current jobs
Lois Tolvinski's past jobs
Designed, oversaw construction, and launched lab operations for 25,000sf site expansion. Led cross-functional operational strategies across biotech R&D, scaling lab infrastructure and processes to support rapid growth across multi-site locations. Executed key initiatives including equipment programs and digital system rollouts (eLab Notebook, equipment monitoring, operations management). Championed leadership development and team enablement efforts, focusing on resource planning, role clarity, and workload distribution to support high-performing teams. Advised C-Suite on operational risk, compliance, and infrastructure investments, balancing scientific rigor with business objectives.
Second FTE hire; reported to CSO and CEO Member of scientific leadership team acting in lieu of CSO [after CSO departure] Assisted with growth of start-up to 12 FTEs and development of operational policies Presented R&D updates to the Board of Directors and the Scientific Advisory Board People manager Portfolio and project management Monitored and reviewed deliverables for projects and programs for cross-functional teams Communicated updates and timelines to internal stakeholders Supported decision-making to drive development of RNA delivery platform technology and preclinical pipeline Managed CRO and CDMO relationships Laboratory and operations management Led 3 complete lab relocations with company expansion Selected and implemented ELN for R&D operations; developed SOPs and training for use Performed space planning and forecasting Managed equipment maintenance and capital purchases Developed lab SOPs and protocols and implemented onboarding training Managed day-to-day operations of lab Lead bioprocess development/nanoparticle production team Upstream and downstream process development: implemented technologies and optimized unit operations for improved yield, recovery, and purity of viral vector-like/virus-like platform technology Oversaw development and validation of analytical methods Led CDMO technology and materials transfer Improved production scale from 30ml to 10L Received Millipore Biotech Advance NA Grant Award, 2023 Mentored and trained interns (from Jefferson Biotechnology MS program and The Wistar Institute’s BTT Program)
ChaESAR Nanoparticle Production Lead Establishment of upstream process for nanoparticle production -Increased scale from 30ml to 10L -Optimization of transfection and harvest conditions to improve titer/yield Establishment of downstream process for nanoparticle production -Implemented ultrafiltration and diafiltration processes Selection and launch of company-wide electronic lab notebook
Kelly Services BPO In vitro pharmacological compound profiling for multiple projects supporting lead discovery and hit-to-lead programs for Oncology and Immunology therapeutic areas Biochemical and cell-based assay development in microplate format (384/1536) Quantitative data analysis and timeline-based data delivery to enable medicinal chemistry SAR studies Cross sector collaboration: Naturals platform, Emerging Science and Innovation
Identifying tangible materials and enabled inventions in unpublished manuscripts; presenting findings to team of interns and business development team Due diligence research Learning the process of developing an intellectual property portfolio Developing an internal blog detailing the work happening at the intersection of business and science
Lab Manager Assist in drafting study sections of IND Developing and optimizing an in vitro target engagement study using UV-activated crosslinking compounds
Lab manager Write and review pre-IND study reports on AlphaScreen and HTRF biochemical assays In vivo studies using GFP and luciferase in an EBV+ tumor mouse model; including tumor implantation, IP injections, oral gavage, live animal imaging, and anesthesia use IVIS Spectrum imaging: 2D, 3D, and micro-CT Software: Living Image for IVIS image acquisition and analysis
Lab Manager Conduct biochemical high throughput screening assays AlphaScreen and HTRF assessing compound disruption of protein/DNA interaction Protein expression in e.coli and purification using affinity chromatography and size-exclusion chromatography Software: Dotmatics for analysis and databasing results; GraphPad Prism
Compound library management of 3000+ novel small molecules synthesized by medicinal chemist collaborators Molecular biology techniques; protein expression and purification, western blotting, SDS-PAGE electrophoresis, cloning