Ranjan Kc
About
Ranjan Kc is from Philadelphia, Pennsylvania, United States. Ranjan works in the following industries: "Biotechnology Research". Ranjan is currently Scientist - Analytical Development at Ocugen, located in Malvern, Pennsylvania, United States. In Ranjan's previous role as a Scientist - Cell & Gene Therapy at Eurofins PSS Insourcing Solutions, Ranjan worked in until Mar 2022. Prior to joining Eurofins PSS Insourcing Solutions, Ranjan was a Research Associate at Children's Hospital of Philadelphia and held the position of Research Associate at Greater Philadelphia Area. Prior to that, Ranjan was a Research Associate at Cleveland Clinic, based in Cleveland/Akron, Ohio Area from Sep 2017 to Jun 2018. Ranjan started working as Postdoctoral Research Fellow at Rush University Medical Center in Oct 2011. From Jun 2006 to Feb 2010, Ranjan was Graduate Research Assistant at Inha university, based in South Korea.
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Ranjan Kc's current jobs
Ranjan Kc's past jobs
• Developed analytical methods and performed cGMP sample testing for biopharmaceutical clients • Analyzed genome integrity and impurities such as residual host cell DNA of AAV drug product • Involved in analytical method development for the determination titer of lenti- and AAV virus using dPCR, Flow cytometry, qPCR and ELISA • Performed drug substance testing to support analytical method development and qualification
• Investigated the role of SOXE transcription factors in the homeostasis of the normal cartilage and in osteoarthritis condition; • Provided innovative ideas for the development of highly needed disease-modifying drugs and tissue regenerative strategies to effectively treat osteoarthritis; • Worked with cutting edge techniques such as scRNA-seq, ChiP-seq and ATAC-seq
• Identified the novel risk factors involved in the development of the osteoarthritis and dissected out the molecular and cellular pathways which had broad impact on developing strategies for translational and cost-effective approaches for the disease treatment. • Led, managed and assisted several research projects that resulted 15+ peer-reviewed articles in the highest-ranked journals in the field. • In collaboration with R&D companies, tested several FDA approved drugs for the treatment of osteoarthritis and pain in preclinical settings. • Generated the key research data that contributed to acquisition of >1.5 million federal funding.
• Solved scientific problems in areas including pancreatitis, diabetes and diabetic nephropathy. • Established several SOPs and methods, managed 2 parallel research projects and collaborated with 3 laboratories with diverse expertise which successfully led to peer-reviewed papers in impactful scientific journals; • Worked as a team leader for lab management, trained and supervised graduate students which led to publications and presentations.