Seithikurippu R Pandi Perumal

Performs all work in accordance with all established regulatory and compliance and safety requirements. Oversees the development of manuscripts for publication, liaising with junior faculties, scholars, as well as junior researchers and reviewing relevant documents and literature to ensure the accuracy of information prior to publication. Oversees and coordinate the project staff for all phases of clinical project management. Establishes and maintains professional standards of communication with colleagues within and outside of NYU Medical Center. Oversees the satisfactory resolution of all departmental issues with internal stakeholders, intervening directly in the most complex or sensitive issues. Takes leadership/managerial role relating to the departmental activities. Participates in the development and communicates specific objectives, translating them into divisional goals and objectives. Conducts performance reviews for direct reports and provides guidance, as appropriate. Works as a member of the team to achieve all outcomes, Performs all work in support of the Institutional Values of Pride, Accountability, Integrity and Diligence; Demonstrates strong and visible support of Institutional values. Provides timely and appropriate reports to the Program Director and Principal Investigators. Recruit, train, develop and manage effectively the ongoing performance of direct reports (e.g. Volunteers), which includes, but is not limited to: Ensuring their duty descriptions are reviewed, signed and sent to Volunteer Services, ensuring that all employees are properly trained and qualified to execute their duties, Providing coaching, feedback and recognition, Responsible to ensure compliance of team members (direct reports) with Safety and Employment policies. All other duties as assigned by the Program Managers and the Principal Investigators.

• Planned, monitored, and coordinated clinical research studies under the direction of the Principal (PI) and Sub Investigators (Sub-PI) and collaborated with other clinical research team to assume responsibility for the overall management and coordination of pharma-sponsored clinical trials focusing on the treatment of insomnia

Scoring of sleep reports

• Participated along with other clinical trial team, in maintaining the timeline and target dates for completion of study milestones and using monitoring resources/reports to deliver milestones on time and budget. • Responsible for the writing and/or reviewing the CRFs (case report forms) adhering to CRF standard operating procetures (SOPs) in compliance with FDA/ICH guidelines. • Assisted in monitoring of clinical studies along with the CRCs and CRAs thus participated in various activities. • Identifying and documents data errors or items requiring clarification and initiates data clarification/validation process after researching source documents. • Worked in collaboration with the CRCs and CRAs and identifies and documents data errors or items requiring clarification on all documents collected for study and initiates data clarification/validation process after researching source documents. • Assisting the Compliance Specialist in Updating the SOPs

Overnight polysomnography (PSG) recording, scoring, teaching of polysomnography, meeting with pharmaceutical/Durable Medical Equipment (DME) company reps, writing, and editing. Worked in close association with the Medical Director for the smooth running of the sleep center at the Division of Epilepsy and Clinical Neurophysiology, Department of Neurology.

Worked with the mentorship of Prof. Rosalind D Cartwright. This position was especially appropriate for my skills and background in clinical polysomnography with a specialty in Rapid Eye Movement (REM) sleep regulation involving depressed patients. The project here was funded by the National Institute of Mental Health (NIMH) that required someone who is specifically able to work independently doing REM sleep interventions with volunteers who are suffering from major depression with a sleep complaint for which they are not currently treated. It was a longitudinal study 5 months with seven sleep assessment for each volunteer. My work involved overnight ploysomnography recording, REM sleep reduction and intervention. I scored all the volunteer's recording, data entry and help with the analysis, and interpreation. Obtained certificate of attendance on, 'Human Research Protections'.

Synaptic mechanisms and circuitry involved in motoneuron control during sleep

Worked on specific projects on Neuronal plasticity during sleep oscillations in corticothalamic networks. Assisted post-docs in laboratory experiements, recording, and data analysis.

At this capacity, I have performed the following functions: provided comprehensive diagnosis of sleep disorders with the help of polysomnography (PSG), and patient care and education. Used good interpersonal skills with an ability to communicate with physicians, laboratory manager, supervisors, and other technical staff discussing PSG technology Laboratory hook-up, equipment operation, Monitoring of specialized medical and electronic equipments. This includes, but not limited to, polygraph, analog polygraph, oximeters, respiratory plethysmography units, positive air pressure machines, tumescence monitors, and laboratory computer systems. Performed sleep monitoring on individuals with suspected sleep pathology. Administered questionnaires (General Health, Pre-Sleep, and Post-Sleep) and performed the tests. Attached necessary devices for monitoring EEG, EOG, EMG, EKG, oximetry, thoracic- and abdominal effort, nasal/oral airflow and nasal/oral pressure. Performed both split-night and full-night continuous positive airway pressure treatment as needed and titrates both CPAP and BiPAP pressure to reduce airway occlusion and attain airway patency. Scored of nocturnal events during PSG recordings for sleep stages, sleep apnea, periodic limb movement in Sleep (PLMS), arousals, and other sleep-related nocturnal parameters as indicated by the study protocol. Performed other job-related duties as required.