Trevor Weden
About
Trevor Weden is from Belmont, California, United States. Trevor works in the following industries: "Biotechnology Research". Trevor is currently Associate Scientist II at Vaxcyte. Trevor also works as Associate Scientist I at Vaxcyte, a job Trevor has held since Nov 2020. In Trevor's previous role as a Immunoassay Research Associate at Vaxcyte, Trevor worked in until Nov 2020. Prior to joining Vaxcyte, Trevor was a Formulation Research Associate at SutroVax Inc. and held the position of Formulation Research Associate. Prior to that, Trevor was a Student Researcher at Oregon State University, based in Corvallis, Oregon Area from Mar 2017 to Dec 2018. Trevor started working as Formulation Intern at Vaxcyte in Jun 2018. From May 2012 to Jan 2018, Trevor was Lifeguard at Ladera Oaks Swim & Tennis Club, based in Portola Valley, CA. Prior to that, Trevor was a Student Intern at Stanford University, based in Palo Alto, CA from Jun 2017 to Sep 2017. Trevor started working as Research Assistant Intern at Armo Biosciences in Redwood City, CA in Jun 2015.
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Trevor Weden's current jobs
Trevor Weden's past jobs
Helped develop key plate-based assays (such as, MSD and Nephelometric) for potency determination of polysaccharide content of Pneumococcal Conjugate Vaccine (PCV) -Optimized and executed DOEs of MSD, an in-process control (IPC) plate based potency assay, method for determination of total saccharide content of multiple serotypes of PCV drug substance (DS) and drug product (DP) -Optimized and executed DOEs of Nephelometry, an IPC plate based potency assay, for determination of total saccharide content of multiple serotypes of PCV -Designed, executed, and analyzed MSD experiments to further implementation to transfer MSD assay to a Contact Research Organization (CRO) and Contact Manufacturing Organization (CMO) -Maintained a relationship with a CRO -Executed routine lab work, lab maintenance, organizing/cleaning glassware, and reagent/consumable stocking
Assisted in designing, optimizing, and executing Anthrone assay methods to determine polysaccharide content of Pneumococcal Conjugate Vaccine (PCV) -Optimized and executed DOEs of Anthrone assay method for determination of total and free saccharide content of multiple serotypes of PCV drug substance and drug product -Optimized and executed DOEs for Sodium Deoxycholate (DOC) precipitation of protein polysaccharide conjugates to measure free polysaccharide content via Anthrone Assay and breakthrough protein concentration via Modified Lowry assay Assisted in executing other formulation development lab work relating to the PCV project Executed In Vivo manufacturing of drug products for assay determination, in-house and for CMOs -Executed DOEs of Modified Lowery assay method for determination of total and free saccharide content of multiple serotypes of PCV DS and DP -Optimized and executed DOEs for Sodium Deoxycholate (DOC) precipitation of protein polysaccharide conjugates to measure breakthrough protein concentration via Modified Lowry assay -Prepared optimized DS-buffer for Conjugation Development Team -Executed routine lab work, lab maintenance, organizing/cleaning glassware, and reagent/consumable stocking
Determination if Cyprinid Herpesvirus III (KHV) can cause persistent infection in vitro. -Executed routine cell culturing of control and treated koi fish fin cells -Executed qPCR testing to detect viral genome within acute koi fish fin cells -Executed ELISA testing to detect KHV infection of koi fish blood samples -Prepared and agarose gel molds for gel-electrophoresis
Assisted in optimizing Anthrone assay methods to determine polysaccharide content of Pneumococcal Conjugate Vaccine (PCV) -Optimized incubation conditions for Anthrone assay method for determination of total and free saccharide content of multiple serotypes of PCV drug substance and drug product -Designed and optimized pipetting conditions for Integra VIAFLO semi-automated pipetter for Anthrone and Modified Lowery assays -Executed routine lab work, lab maintenance, organizing/cleaning glassware, and reagent/consumable stocking
Efficacy and Mechanisms of Metformin Therapy in Established Experimental Abdominal Aortic Aneurysms (AAA) -Read and recorded daily systolic and diastolic readings for lab mice -Prepared mice for ultrasonographic assessment of aortic diameter during treatment -Prepared and executed histological examination of aorta from sacrificial mice -Sectioned and stained slides using a microtome and lipid staining techniques